Publication:
The Biology of Retinopathy of Prematurity

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2013

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Elsevier BV
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Smith, Lois E., Anna-Lena Hard, and Ann Hellström. 2013. The Biology of Retinopathy of Prematurity. Clinics in Perinatology 40, no. 2: 201–214. doi:10.1016/j.clp.2013.02.002.

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Abstract

Retinopathy of prematurity occurs because the retina of a preterm infant at birth is incompletely vascularized, and if the postnatal environment does not match the in utero environment that supported retinal development, the vessels and neural retina will not grow normally. Risk factors determined from many clinical studies and animal studies fall into 2 categories: prenatal factors and postnatal factors.

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oxygen, IGF-I, omega-3 polyunsaturated fatty acids, postnatal weight gain, erythropoietin

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