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Unfolding the Folding Problem of the Cerebral Cortex: Movin’ and Groovin’

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2017

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Elsevier BV
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Itoh, Yasuhiro, Alexandros Poulopoulos, and Jeffrey D. Macklis. 2017. “Unfolding the Folding Problem of the Cerebral Cortex: Movin’ and Groovin’.” Developmental Cell 41 (4) (May): 332–334. doi:10.1016/j.devcel.2017.05.011.

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Abstract

The development of reproducible folding in the gyrencephalic cerebral cortex is a topic of great interest to neuroscientists. In a recent paper in Cell, del Toro et al. (2017) show that changing the adhesive properties of neurons in the normally lissencephalic mouse cortex leads to the formation of stereotyped folding.

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