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Human Resources for Treating HIV/AIDS: Are the Preventive Effects of Antiretroviral Treatment a Game Changer?

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2016

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Public Library of Science
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Bärnighausen, Till, David E. Bloom, and Salal Humair. 2016. “Human Resources for Treating HIV/AIDS: Are the Preventive Effects of Antiretroviral Treatment a Game Changer?” PLoS ONE 11 (10): e0163960. doi:10.1371/journal.pone.0163960. http://dx.doi.org/10.1371/journal.pone.0163960.

Abstract

Shortages of human resources for treating HIV/AIDS (HRHA) are a fundamental barrier to reaching universal antiretroviral treatment (ART) coverage in developing countries. Previous studies suggest that recruiting HRHA to attain universal ART coverage poses an insurmountable challenge as ART significantly increases survival among HIV-infected individuals. While new evidence about ART’s prevention benefits suggests fewer infections may mitigate the challenge, new policies such as treatment-as-prevention (TasP) will exacerbate it. We develop a mathematical model to analytically study the net effects of these countervailing factors. Using South Africa as a case study, we find that contrary to previous results, universal ART coverage is achievable even with current HRHA numbers. However, larger health gains are possible through a surge-capacity policy that aggressively recruits HRHA to reach universal ART coverage quickly. Without such a policy, TasP roll-out can increase health losses by crowding out sicker patients from treatment, unless a surge capacity exclusively for TasP is also created.

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Biology and Life Sciences, Microbiology, Medical Microbiology, Microbial Pathogens, Viral Pathogens, Immunodeficiency Viruses, HIV, Medicine and Health Sciences, Pathology and Laboratory Medicine, Pathogens, Organisms, Viruses, Biology and life sciences, RNA viruses, Retroviruses, Lentivirus, Immunology, Vaccination and Immunization, Antiviral Therapy, Antiretroviral Therapy, Public and Occupational Health, Preventive Medicine, Medicine and health sciences, Epidemiology, HIV epidemiology, Health Care, Health Care Policy, People and places, Geographical locations, Africa, South Africa, Health Care Providers, Medical Doctors, Physicians, People and Places, Population Groupings, Professions, Infectious diseases, Viral diseases, HIV infections, Health Systems Strengthening

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