Publication: Ebola Virus Epidemiology and Evolution in Nigeria
Open/View Files
Date
2016
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
Oxford University Press
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Folarin, O. A., D. Ehichioya, S. F. Schaffner, S. M. Winnicki, S. Wohl, P. Eromon, K. L. West, et al. 2016. “Ebola Virus Epidemiology and Evolution in Nigeria.” The Journal of Infectious Diseases 214 (Suppl 3): S102-S109. doi:10.1093/infdis/jiw190. http://dx.doi.org/10.1093/infdis/jiw190.
Research Data
Abstract
Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.
Description
Other Available Sources
Keywords
Ebola, genomic, phylogeny, epidemiology, Nigeria, sequencing, outbreak
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service