Publication: Cautionary optimism: caffeine and Parkinson’s disease risk
Open/View Files
Date
2016
Published Version
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
The Harvard community has made this article openly available. Please share how this access benefits you.
Citation
Sokol, Leonard L., Michael J. Young, Alberto J. Espay, and Ronald B. Postuma. 2016. “Cautionary optimism: caffeine and Parkinson’s disease risk.” Journal of Clinical Movement Disorders 3 (1): 7. doi:10.1186/s40734-016-0037-8. http://dx.doi.org/10.1186/s40734-016-0037-8.
Research Data
Abstract
Most Parkinson’s disease (PD) patients present without known family history and without a diagnosed prodromal phase, underscoring the difficulty of employing primary (neuroprevention) and secondary (neuroprotection) preventions. In cases of monogenic forms, however, potential gene-carrying family members of a proband could engage in neuroprevention, such as exercise or diet modifications, to attenuate the risk of, or delay, disease development. However, a historical lack of recognized disease-modifying interventions has limited clinicians’ ability to recommend reliable preventive measures in caring for at-risk populations. We briefly analyze the first retrospective study to examine caffeine consumption and PD risk in a LRRK2 R1628P cohort.
Description
Other Available Sources
Keywords
Parkinson’s disease, LRRK2, Caffeine, Risk factors
Terms of Use
This article is made available under the terms and conditions applicable to Other Posted Material (LAA), as set forth at Terms of Service