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Comparative effectiveness of single versus multiple tablet antiretroviral therapy regimens in clinical HIV practice

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2017

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Wolters Kluwer Health
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Drozd, D. R., M. S. Saag, A. O. Westfall, W. C. Mathews, R. Haubrich, S. L. Boswell, S. R. Cole, et al. 2017. “Comparative effectiveness of single versus multiple tablet antiretroviral therapy regimens in clinical HIV practice.” Medicine 96 (14): e6275. doi:10.1097/MD.0000000000006275. http://dx.doi.org/10.1097/MD.0000000000006275.

Abstract

Abstract We determined risk of virologic failure (VF) in individuals initiating tenofovir/emtricitabine/efavirenz as single versus multiple tablet regimens (MTR). We found no significant difference in the risk of VF, though did observe a trend toward more VF and M184 V mutations among persons initiating MTR. Temporal trends in care may have confounded results.

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Observational Study, ART, atripla, comparative effectiveness, HIV, single tablet regimen

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