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An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease

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2015-08-12

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American Association for the Advancement of Science (AAAS)
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Zhang, Sufeng, Joerg Ermann, Marc Succi, Allen Zhou, Matthew Hamilton, Bonnie Cao, Joshua Korzenik et al. "An inflammation-targeting hydrogel for local drug delivery in inflammatory bowel disease." Sci. Transl. Med. 7, no. 300 (2015): 300ra128. DOI: 10.1126/scitranslmed.aaa5657

Abstract

A hydrogel binds to inflamed tissues, delivering therapeutics locally and reducing systemic drug exposure in mouse models of inflammatory bowel disease.

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General Medicine

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