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Secular Trends in Helicobacter pylori Seroprevalence in Adults in the United States: Evidence for Sustained Race/Ethnic Disparities

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2011

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10.1093/aje/kwr288

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Oxford University Press (OUP)
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Grad, Y. H., M. Lipsitch, and A. E. Aiello. 2011. Secular Trends in Helicobacter Pylori Seroprevalence in Adults in the United States: Evidence for Sustained Race/Ethnic Disparities. American Journal of Epidemiology 175, no. 1: 54–59. doi:10.1093/aje/kwr288.

Abstract

Helicobacter pylori seroprevalence levels in US adults participating in the continuous National Health and Nutrition Examination Survey (1999-2000) increased with age in all racial/ethnic groups, with significantly higher age-standardized levels in Mexican Americans (64.0%, 95% confidence interval (CI): 58.8, 69.2) and non-Hispanic blacks (52.0%, 95% CI: 48.3, 55.7) compared with non-Hispanic whites (21.2%, 95% CI: 19.1, 23.2). Although seroprevalence levels remained similar to those found in National Health and Nutrition Examination Surveys from 1988 to 1991 among non-Hispanic blacks and Mexican Americans, they were significantly lower in non-Hispanic whites, especially at older ages. The factors driving the decline in H. pylori seroprevalence appear to be acting preferentially on the non-Hispanic white population.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244610/

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http://nrs.harvard.edu/urn-3:HUL.InstRepos:37147300

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