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Understanding anti-leukemia responses to donor lymphocyte infusion

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2014

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Landes Bioscience
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Bachireddy, Pavan, and Catherine J Wu. 2014. “Understanding anti-leukemia responses to donor lymphocyte infusion.” Oncoimmunology 3 (1): e28187. doi:10.4161/onci.28187. http://dx.doi.org/10.4161/onci.28187.

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Abstract

Donor lymphocyte infusion (DLI) is an established and potentially curative immune therapy for relapsed leukemia after hematopoietic stem cell transplant (HSCT). Herein, we describe the utility of DLI as a tractable model system to glean fresh insights into understanding and predicting effective anti-leukemia immunity.

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T cell exhaustion, donor lymphocyte infusion, CML, stem cell transplantation, tumor-infiltrating lymphocytes

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