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Design and Characterization of a Stealth Immunoliposome Encapsulating a Large Molecule Biotherapeutic (Antibody)

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2017-04-13

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Njenga, Moses. 2017. Design and Characterization of a Stealth Immunoliposome Encapsulating a Large Molecule Biotherapeutic (Antibody). Master's thesis, Harvard Extension School.

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Abstract

This thesis project will endeavor to solve the obstacles around synthesis of Immunoliposomes loaded with an antibody therapeutic. Most steps in the preparation of liposomes in most of the methods include harsh conditions that are not amenable for antibody therapeutic entrapment.This study primarily focuses on preparation of liposomes using the Dry Film Hydration method to prepare liposomes with the least amounts of organic solvents.

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Biology, General, Biology, General

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