Publication: Narrowing the spectrum: the new frontier of precision antimicrobials
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Date
2017
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BioMed Central
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Paharik, Alexandra E., Henry L. Schreiber, Caitlin N. Spaulding, Karen W. Dodson, and Scott J. Hultgren. 2017. “Narrowing the spectrum: the new frontier of precision antimicrobials.” Genome Medicine 9 (1): 110. doi:10.1186/s13073-017-0504-3. http://dx.doi.org/10.1186/s13073-017-0504-3.
Abstract
Editorial summary Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial microbial communities inhabiting humans. To combat antibiotic resistance and protect these communities, new precision antimicrobials must be engineered to target specific pathogens.
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