Publication: Dissecting the mammary gland one cell at a time
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Date
2018
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Nature Publishing Group UK
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Cristea, Simona, and Kornelia Polyak. 2018. “Dissecting the mammary gland one cell at a time.” Nature Communications 9 (1): 2473. doi:10.1038/s41467-018-04905-2. http://dx.doi.org/10.1038/s41467-018-04905-2.
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Abstract
Dissecting cellular differentiation hierarchies in the mammary gland is a prerequisite for understanding both normal development and malignant transformation during tumorigenesis and tumor cell-of-origin. To achieve these goals, several recent papers utilized single cell RNA-seq and lineage tracing to improve our understanding of the composition of the mammary epithelium at different developmental stages.
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