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Barriers and facilitators to antiretroviral therapy adherence among Peruvian adolescents living with HIV: A qualitative study

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2018

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Public Library of Science
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Galea, Jerome T., Milagros Wong, Maribel Muñoz, Emiliano Valle, Segundo R. Leon, Dayana Díaz Perez, Lenka Kolevic, and Molly Franke. 2018. “Barriers and facilitators to antiretroviral therapy adherence among Peruvian adolescents living with HIV: A qualitative study.” PLoS ONE 13 (2): e0192791. doi:10.1371/journal.pone.0192791. http://dx.doi.org/10.1371/journal.pone.0192791.

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Abstract

AIDS deaths among adolescents are increasing globally. This qualitative study investigated the barriers and facilitators to cART adherence among Peruvian adolescents living with HIV. Guided by a social ecological model, we analyzed transcripts from 24 psychosocial support groups for HIV-positive adolescents aged 13–17 years and 15 individual, in-depth interviews with cART providers and caregivers to identify the barriers and facilitators to cART adherence at the individual, family/caregiver and hospital levels. Most barriers and facilitators to cART adherence clustered at the individual and family/caregiver levels, centering on support provided to adolescents; history of declining health due to suboptimal cART adherence; side effects from antiretroviral drugs; and cART misinformation. Interventions to support adolescent HIV cART adherence should begin at the individual and family/caregiver levels and include an educational component. No adolescent living with HIV should die from AIDS in an era of accessible cART.

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People and Places, Population Groupings, Age Groups, Children, Adolescents, Families, Biology and Life Sciences, Microbiology, Medical Microbiology, Microbial Pathogens, Viral Pathogens, Immunodeficiency Viruses, HIV, Medicine and Health Sciences, Pathology and Laboratory Medicine, Pathogens, Organisms, Viruses, Biology and life sciences, RNA viruses, Retroviruses, Lentivirus, Health Care, Psychological and Psychosocial Issues, Medicine and health sciences, Infectious diseases, Viral diseases, HIV infections, Pediatrics, Pharmacology, Drugs, Antimicrobials, Antivirals, Antiretrovirals, Microbial Control, Virology, Ecology, Theoretical Ecology, Ecology and Environmental Sciences, Psychology, Emotions, Social Sciences

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