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Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses

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2017

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John Wiley and Sons Inc.
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Teixeira, A. A., S. Marchiò, E. Dias‐Neto, D. N. Nunes, I. T. da Silva, B. Chackerian, M. Barry, et al. 2017. “Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses.” EMBO Molecular Medicine 9 (10): 1327-1330. doi:10.15252/emmm.201708072. http://dx.doi.org/10.15252/emmm.201708072.

Abstract

The hypothesis is discussed that prostate cancer marker lncRNA PCA3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.

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Opinion, Cancer, Microbiology, Virology & Host Pathogen Interaction, Urogenital System

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