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Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing

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2017

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Oxford University Press
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Piantadosi, A., S. Kanjilal, V. Ganesh, A. Khanna, E. P. Hyle, J. Rosand, T. Bold, et al. 2017. “Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing.” Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 66 (5): 789-792. doi:10.1093/cid/cix792. http://dx.doi.org/10.1093/cid/cix792.

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Abstract

Abstract We describe a patient with severe and progressive encephalitis of unknown etiology. We performed rapid metagenomic sequencing from cerebrospinal fluid and identified Powassan virus, an emerging tick-borne flavivirus that has been increasingly detected in the United States.

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Powassan virus, encephalitis, metagenomic sequencing

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