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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update

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2017

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MDPI
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Catassi, C., A. Alaedini, C. Bojarski, B. Bonaz, G. Bouma, A. Carroccio, G. Castillejo, et al. 2017. “The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update.” Nutrients 9 (11): 1268. doi:10.3390/nu9111268. http://dx.doi.org/10.3390/nu9111268.

Abstract

Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS). New research has specifically addressed prevalence, immune mechanisms, the recognition of non-immunoglobulin E (non-IgE) wheat allergy and overlap of NCGS with irritable bowel syndrome (IBS)-type symptoms. This review article will provide clinicians with an update that directly impacts on the management of a subgroup of their IBS patients whose symptoms are triggered by wheat ingestion.

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gluten sensitivity, celiac disease, wheat allergy, gluten-related disorders, gluten-free diet, amylase-trypsin inhibitors (ATIs)

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