Publication: Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis Isolates
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Date
2005
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American Society for Microbiology
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Xie, Z., N. Siddiqi, and E. J. Rubin. 2005. “Differential Antibiotic Susceptibilities of Starved Mycobacterium Tuberculosis Isolates.” Antimicrobial Agents and Chemotherapy 49 (11): 4778–80. https://doi.org/10.1128/aac.49.11.4778-4780.2005.
Abstract
We compared the efficacies of 17 agents against rapidly growing and starved Mycobacterium tuberculosis H37Rv. Few compounds have significant activity at attainable concentrations. However, two phenothiazine compounds at similar concentrations were bactericidal for starved and growing cells. These drugs appear to target a process important in both replicating and nonreplicating bacteria.
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