Publication: Red Si-rhodamine drug conjugates enable imaging in GFP cells
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Date
2014
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Royal Society of Chemistry
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Kim, Eunha, Katherine S. Yang, Randy J. Giedt, and Ralph Weissleder. 2014. “Red Si–rhodamine Drug Conjugates Enable Imaging in GFP Cells.” Chemical Communications 50 (34): 4504. https://doi.org/10.1039/c4cc00144c.
Abstract
Here we evaluated a series of Si-derivatized rhodamine (SiR) dyes for their ability to visualize a model drug in live cells. We show that a charge neutral SiR derivative (but not others) can indeed be used to follow the intracellular location of the model therapeutic drug in GFP cells.
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