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Mixed-Strain Mycobacterium tuberculosis Infections among Patients Dying in a Hospital in KwaZulu-Natal, South Africa

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2011

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American Society for Microbiology
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Cohen, T., D. Wilson, K. Wallengren, E. Y. Samuel, and M. Murray. 2010. “Mixed-Strain Mycobacterium Tuberculosis Infections among Patients Dying in a Hospital in KwaZulu-Natal, South Africa.” Journal of Clinical Microbiology 49 (1): 385–88. https://doi.org/10.1128/jcm.01378-10.

Abstract

We performed spoligotyping and 24-locus mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) typing on M. tuberculosis culture-positive biopsy specimens collected from adults dying in a hospital in KwaZulu-Natal. Of 56 culture-positive samples genotyped, we detected mixed strains in five (9%) and clonal heterogeneity in an additional four (7%).

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