Publication: Assisted Reproductive Technology: Ethical and Economic Inquiries
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2019-10-25
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Obayan, Ifeoluwa. 2019. Assisted Reproductive Technology: Ethical and Economic Inquiries. Bachelor's thesis, Harvard College.
Abstract
Hatching is an integral step in preimplantation embryo development, and issues during hatching may lower the chance of embryo implantation in the womb. The mechanics of the embryo hatching out of the restricting zona pellucida places physical stress on the embryo, leading to DNA double-strand breakage. While hatched embryos did not show signs of more DNA DSB compared to unhatched embryos, the highly concentrated regions were mainly found in the outer layer of the cell.
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