Carbon–Fluorine Bond Formation
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Furuya, Takeru, Christian A. Kuttruff, and Tobias Ritter. 2008. Carbon–fluorine bond formation. Current Opinion in Drug Discovery and Development 11(6): 803–819.Abstract
We present a selection of carbon–fluorine bond formations that have been developed in the recent past. An overview of the most common fluorination reagents is followed by fluorination reactions organized by reactivity. We have distinguished between nucleophilic and electrophilic fluorinations as well as aliphatic and aromatic fluorinations. Each section is divided into more specific reaction classes and examples for syntheses of pharmaceuticals, \(^{18}\)F-radiolabeling, and mechanistic investigations are provided.Terms of Use
This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAPCitable link to this page
http://nrs.harvard.edu/urn-3:HUL.InstRepos:8301597
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