Browsing by Author "Aliprantis, Antonios"

Now showing items 1-5 of 5

    • Anion Exchanger 2 Regulates Dectin-1-Dependent Phagocytosis and Killing of Candida albicans 

      Urso, Katia; Charles, Julia F.; Shull, Gary E.; Aliprantis, Antonios O.; Balestrieri, Barbara (Public Library of Science, 2016)
      Anion exchanger 2 (Ae2; gene symbol, Slc4a2) is a plasma membrane Cl-/HCO3- exchanger expressed in the gastrointestinal tract, kidney and bone. We have previously shown that Ae2 is required for the function of osteoclasts, ...

    • Calcineurin Regulates Innate Antifungal Immunity in Neutrophils 

      Greenblatt, Matthew Blake; Aliprantis, Antonios O.; Hu, Bella; Glimcher, Laurie Hollis (Rockefeller University Press, 2010)
      Patients taking immunosuppressive drugs, like cyclosporine A (CsA), that inhibit calcineurin are highly susceptible to disseminated fungal infections, although it is unclear how these drugs suppress resistance to these ...

    • Graft versus Host Disease in the Bone Marrow, Liver and Thymus Humanized Mouse Model 

      Greenblatt, Matthew Blake; Vbranac, Vladimir; Tivey, Trevor; Tsang, Kelly; Tager, Andrew Martin; Aliprantis, Antonios O. (Public Library of Science, 2012)
      Mice bearing a “humanized” immune system are valuable tools to experimentally manipulate human cells in vivo and facilitate disease models not normally possible in laboratory animals. Here we describe a form of GVHD that ...

    • Mass spectrometry assays of plasma biomarkers to predict radiographic progression of knee osteoarthritis 

      Ritter, Susan Y; Collins, Jamie; Krastins, Bryan; Sarracino, David; Lopez, Mary; Losina, Elena; Aliprantis, Antonios O (BioMed Central, 2014)
      Introduction: Biomarkers to identify osteoarthritis (OA) patients at risk for disease progression are needed. As part of a proteomic analysis of knee synovial fluid from normal and OA patients, differentially expressed ...

    • Sex-Specific Protection of Osteoarthritis by Deleting Cartilage Acid Protein 1 

      Ge, Xianpeng; Ritter, Susan Y.; Tsang, Kelly; Shi, Ruirui; Takei, Kohtaro; Aliprantis, Antonios O. (Public Library of Science, 2016)
      Cartilage acidic protein 1 (CRTAC1) was recently identified as an elevated protein in the synovial fluid of patients with osteoarthritis (OA) by a proteomic analysis. This gene is also upregulated in both human and mouse ...