Browsing Faculty of Arts and Sciences by Keyword "diabetes and endocrinology"

Now showing items 1-2 of 2

    • All β Cells Contribute Equally to Islet Growth and Maintenance 

      Brennand, Kristen; Huangfu, Danwei; Melton, Douglas (Public Library of Science, 2007)
      In healthy adult mice, the β cell population is not maintained by stem cells but instead by the replication of differentiated β cells. It is not known, however, whether all cells contribute equally to growth and maintenance, ...

    • Interpreting Metabolomic Profiles using Unbiased Pathway Models 

      Hunter, Luke; Pare, Guillaume; Vasan, Ramachandran S.; Lewis, Gregory D; Wang, Thomas Jue-Fuu; Chasman, Daniel Ian; Gerszten, Robert Edgardo; Deo, Rahul Chandrakant; Roth, Frederick Phillip (Public Library of Science, 2010)
      Human disease is heterogeneous, with similar disease phenotypes resulting from distinct combinations of genetic and environmental factors. Small-molecule profiling can address disease heterogeneity by evaluating the ...