Browsing Harvard Medical School by Author "Liewald, David C"

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    • Genetic diversity is a predictor of mortality in humans 

      Bihlmeyer, Nathan A; Brody, Jennifer A; Smith, Albert Vernon; Lunetta, Kathryn L; Nalls, Mike; Smith, Jennifer A; Tanaka, Toshiko; Davies, Gail; Yu, Lei; Mirza, Saira Saeed; Teumer, Alexander; Coresh, Josef; Pankow, James S; Franceschini, Nora; Scaria, Anish; Oshima, Junko; Psaty, Bruce M; Gudnason, Vilmundur; Eiriksdottir, Gudny; Harris, Tamara B; Li, Hanyue; Karasik, David; Kiel, Douglas P; Garcia, Melissa; Liu, Yongmei; Faul, Jessica D; Kardia, Sharon LR; Zhao, Wei; Ferrucci, Luigi; Allerhand, Michael; Liewald, David C; Redmond, Paul; Starr, John M; De Jager, Philip L; Evans, Denis A; Direk, Nese; Ikram, Mohammed Arfan; Uitterlinden, André; Homuth, Georg; Lorbeer, Roberto; Grabe, Hans J; Launer, Lenore; Murabito, Joanne M; Singleton, Andrew B; Weir, David R; Bandinelli, Stefania; Deary, Ian J; Bennett, David A; Tiemeier, Henning; Kocher, Thomas; Lumley, Thomas; Arking, Dan E (BioMed Central, 2014)
      Background: It has been well-established, both by population genetics theory and direct observation in many organisms, that increased genetic diversity provides a survival advantage. However, given the limitations of both ...

    • Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits 

      Pankratz, Nathan; Schick, Ursula M; Zhou, Yi; Zhou, Wei; Ahluwalia, Tarunveer Singh; Allende, Maria Laura; Auer, Paul L; Bork-Jensen, Jette; Brody, Jennifer A; Chen, Ming-Huei; Clavo, Vinna; Eicher, John D; Grarup, Niels; Hagedorn, Elliott J; Hu, Bella; Hunker, Kristina; Johnson, Andrew D; Leusink, Maarten; Lu, Yingchang; Lyytikäinen, Leo-Pekka; Manichaikul, Ani; Marioni, Riccardo E; Nalls, Mike A; Pazoki, Raha; Smith, Albert Vernon; van Rooij, Frank J A; Yang, Min-Lee; Zhang, Xiaoling; Zhang, Yan; Asselbergs, Folkert W; Boerwinkle, Eric; Borecki, Ingrid B; Bottinger, Erwin P; Cushman, Mary; de Bakker, Paul I W; Deary, Ian J; Dong, Liguang; Feitosa, Mary F; Floyd, James S; Franceschini, Nora; Franco, Oscar H; Garcia, Melissa E; Grove, Megan L; Gudnason, Vilmundur; Hansen, Torben; Harris, Tamara B; Hofman, Albert; Jackson, Rebecca D; Jia, Jia; Kähönen, Mika; Launer, Lenore J; Lehtimäki, Terho; Liewald, David C; Linneberg, Allan; Liu, Yongmei; Loos, Ruth J F; Nguyen, Vy M; Numans, Mattijs E; Pedersen, Oluf; Psaty, Bruce M; Raitakari, Olli T; Rich, Stephen S; Rivadeneira, Fernando; Di Sant, Amanda M Rosa; Rotter, Jerome I; Starr, John M; Taylor, Kent D; Thuesen, Betina Heinsbæk; Tracy, Russell P; Uitterlinden, Andre G; Wang, Jiansong; Wang, Judy; Dehghan, Abbas; Huo, Yong; Cupples, L Adrienne; Wilson, James G; Proia, Richard L; Zon, Leonard I; O’Donnell, Christopher J; Reiner, Alex P; Ganesh, Santhi K (2016)
      Hematologic measures such as hematocrit and white blood cell (WBC) count are heritable and clinically relevant. Erythrocyte and WBC phenotypes were analyzed with Illumina HumanExome BeadChip genotypes in 52,531 individuals ...