Browsing Harvard Medical School by Author "Altemose, Nicolas"

Now showing items 1-2 of 2

    • Non-crossover gene conversions show strong GC bias and unexpected clustering in humans 

      Williams, Amy L; Genovese, Giulio; Dyer, Thomas; Altemose, Nicolas; Truax, Katherine; Jun, Goo; Patterson, Nick; Myers, Simon R; Curran, Joanne E; Duggirala, Ravi; Blangero, John; Reich, David; Przeworski, Molly (eLife Sciences Publications, Ltd, 2015)
      Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in ...

    • Using population admixture to help complete maps of the human genome 

      Genovese, Giulio; Handsaker, Robert E.; Li, Heng; Altemose, Nicolas; Lindgren, Amelia M.; Chambert, Kimberly; Pasaniuc, Bogdan; Price, Alkes L.; Reich, David; Morton, Cynthia C.; Pollak, Martin R.; Wilson, James G.; McCarroll, Steven A. (2013)
      Tens of millions of base pairs of euchromatic human genome sequence, including many protein-coding genes, have no known location in the human genome. We describe an approach for localizing the human genome's missing pieces ...