Browsing Harvard Medical School by Author "Borges, Leonardo P."
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VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
Cursiefen, Claus; Chen, Lu; Borges, Leonardo P.; Jackson, David; Cao, Jingtai; Radziejewski, Czeslaw; D'Amore, Patricia Ann; Dana, Reza; Wiegand, Stanley J.; Streilein, J. Wayne (American Society for Clinical Investigation, 2004)Lymphangiogenesis, an important initial step in tumor metastasis and transplant sensitization, is mediated by the action of VEGF-C and -D on VEGFR3. In contrast, VEGF-A binds VEGFR1 and VEGFR2 and is an essential hemangiogenic ...