Browsing Harvard Medical School by Author "Li, Juying"
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Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity
Li, Juying; Yin, Helen L.; Yuan, Junying (Rockefeller University Press, 2008)Caspase-1 and caspase-11 are proinflammatory caspases that regulate cytokine production and leukocyte migration during pathogen infection. In an attempt to identify new intracellular regulators of caspase-11, we found that ... -
YY1 Regulates Melanocyte Development and Function by Cooperating with MITF
Li, Juying; Bell, Robert J. A.; Liu, Huifei; Love, Kevin T.; Larue, Lionel; Song, Jun S.; Tran, Thanh-Nga Trinh; Haq, Rizwan; Langer, Robert S.; Anderson, Daniel Griffith; Fisher, David Erich (Public Library of Science, 2012)Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed ...