Browsing Harvard Medical School by Author "Brooks, Jill M."
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T Cell Detection of a B-Cell Tropic Virus Infection: Newly-Synthesised versus Mature Viral Proteins as Antigen Sources for CD4 and CD8 Epitope Display
Mackay, Laura K.; Long, Heather M.; Brooks, Jill M.; Taylor, Graham S.; Leung, Carol S.; Chen, Adrienne; Wang, Frederick Chi-Shing; Rickinson, Alan B. (Public Library of Science, 2009)Viruses that naturally infect cells expressing both MHC I and MHC II molecules render themselves potentially visible to both CD8+ and CD4+ T cells through the de novo expression of viral antigens. Here we use one such ...