Browsing Harvard Medical School by Author "Harmon, Brennan"

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    • Tissue-Specific Alternative Splicing of TCF7L2 

      Prokunina-Olsson, Ludmila; Welch, Cullan; Hansson, Ola; Adhikari, Neeta; Usher, Nicolle; Tong, Maurine; Sprau, Andrew; Swift, Amy; Bonnycastle, Lori L.; Erdos, Michael R.; Harmon, Brennan; Kotova, Olga; Hoffman, Eric P.; Groop, Leif; Boehnke, Michael; Collins, Francis S.; Hall, Jennifer L.; Scott, Laura J.; He, Zhi; Saxena, Richa; Altshuler, David Matthew (Oxford University Press, 2009)
      Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been identified as the strongest genetic risk factors for type 2 diabetes (T2D). However, the mechanisms by which these non-coding variants increase ...