Browsing Harvard Medical School by Title
Now showing items 473-492 of 18433
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Advances in translational bioinformatics facilitate revealing the landscape of complex disease mechanisms
(BioMed Central, 2014)Advances of high-throughput technologies have rapidly produced more and more data from DNAs and RNAs to proteins, especially large volumes of genome-scale data. However, connection of the genomic information to cellular ... -
Advances in Tumor Screening, Imaging, and Avatar Technologies for High-Grade Serous Ovarian Cancer
(Frontiers Media S.A., 2014)The majority of high-grade serous ovarian carcinoma cases are detected in advanced stages when treatment options are limited. Surgery is less effective at eradicating the disease when it is widespread, resulting in high ... -
Advances in understanding cartilage remodeling
(F1000Research, 2015)Cartilage remodeling is currently among the most popular topics in osteoarthritis research. Remodeling includes removal of the existing cartilage and replacement by neo-cartilage. As a loss of balance between removal and ... -
Advances in Wearable Technology and Applications in Physical Medicine and Rehabilitation
(BioMed Central, 2005)The development of miniature sensors that can be unobtrusively attached to the body or can be part of clothing items, such as sensing elements embedded in the fabric of garments, have opened countless possibilities of ... -
Advancing biomedical imaging
(National Academy of Sciences, 2015)Imaging reveals complex structures and dynamic interactive processes, located deep inside the body, that are otherwise difficult to decipher. Numerous imaging modalities harness every last inch of the energy spectrum. ... -
Advancing Cancer Systems Biology: Introducing the Center for the Development of a Virtual Tumor, CViT
(Libertas Academica, 2007)Integrative cancer biology research relies on a variety of data-driven computational modeling and simulation methods and techniques geared towards gaining new insights into the complexity of biological processes that are ... -
Advancing medicine one research note at a time: the educational value in clinical case reports
(BioMed Central, 2012)A case report—a brief written note that describes unique aspects of a clinical case—provides a significant function in medicine given its rapid, succinct, and educational contributions to scientific literature and clinical ... -
Advancing Surveillance of Chronic and Non-Communicable Disease—A Path Forward
(University of Illinois at Chicago Library, 2013)Objective: To characterize current and future approaches to surveillance of chronic and non-communicable diseases and establish the agenda for both methodological and condition-specific progress. Introduction: Major global ... -
Advancing the science of ventilator-associated pneumonia surveillance
(BioMed Central, 2012)The landmark Study on the Efficacy of Nosocomial Infection Control definitively demonstrated that infection surveillance and control programs prevent hospital-acquired infections. The rise of public reporting, benchmarking, ... -
Advantages and Limitations of Anticipating Laboratory Test Results from Regression- and Tree-Based Rules Derived from Electronic Health-Record Data
(Public Library of Science, 2014)Laboratory testing is the single highest-volume medical activity, making it useful to ask how well one can anticipate whether a given test result will be high, low, or within the reference interval (“normal”). We analyzed ... -
Advantages of Percent Weight Loss as a Method of Reporting Weight Loss after Roux-en-Y Gastric Bypass
(2012)Objective: Although Roux-en-Y gastric bypass (RYGB) is a generally effective treatment for severe obesity, weight loss (WL) after this operation is highly variable. Accurate predictors of outcome would thus be useful in ... -
Adverse Drug Events in Ambulatory Care
(Massachusetts Medical Society, 2003-04-17)BACKGROUND Adverse events related to drugs occur frequently among inpatients, and many of these events are preventable. However, few data are available on adverse drug events among outpatients. We conducted a study to ... -
Adverse Drug Events in Pediatric Outpatients
(Elsevier BV, 2007-09)Objective.-To determine rates and types of adverse drug events (ADEs) in the pediatric ambulatory setting. Methods.-A prospective cohort study at 6 office practices in the greater Boston area was conducted over 2-month ... -
Adverse drug events in the outpatient setting: an 11-year national analysis
(Wiley-Blackwell, 2010)Purpose: Adverse drug events (ADEs) are a common complication of medical care resulting in high morbidity and medical expenditure. Population level estimates of outpatient ADEs are limited. Our objective was to provide ... -
Adverse Events Associated with Sedative and Anesthetic Drugs in Pediatric Patients
(2023-05-11)OVERVIEW The use of sedatives and anesthetics in pediatric critical care settings and operating rooms is inevitable. Sedation is required in critically ill pediatric patients to aid ventilation and decrease anxiety and ... -
Adverse Outcomes After Hospitalization and Delirium in Persons With Alzheimer Disease
(American College of Physicians, 2012)BACKGROUND: Hospitalization, frequently complicated by delirium, can be a life-changing event for patients with Alzheimer disease (AD). OBJECTIVE: To determine risks for institutionalization, cognitive decline, or death ... -
Adverse Outcomes of Underuse of β-Blockers in Elderly Survivors of Acute Myocardial Infarction
(American Medical Association (AMA), 1997)Objectives. —To study determinants and adverse outcomes (mortality and rehospitalization) of β-blocker underuse in elderly patients with myocardial infarction; and whether the relative risks (RRs) of survival associated ... -
Afatinib versus methotrexate in older patients with second-line recurrent and/or metastatic head and neck squamous cell carcinoma: subgroup analysis of the LUX-Head & Neck 1 trial†
(Oxford University Press, 2016)Background: In the phase III LUX-Head & Neck 1 (LHN1) trial, afatinib significantly improved progression-free survival (PFS) versus methotrexate in recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma ... -
Affective and Neural Reactivity to Criticism in Individuals High and Low on Perceived Criticism
(Public Library of Science, 2012)People who have remitted from depression are at increased risk for relapse if they rate their relatives as being critical of them on a simple self-report measure of Perceived Criticism (PC). To explore neural mechanisms ... -
Affinity flow fractionation of cells via transient interactions with asymmetric molecular patterns
(Nature Publishing Group, 2013)Flow fractionation of cells using physical fields to achieve lateral displacement finds wide applications, but its extension to surface molecule-specific separation requires labeling. Here we demonstrate affinity flow ...