Browsing Harvard Medical School by Keyword "Comparative effectiveness"
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A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline
(BioMed Central, 2016)Common diseases like diabetes, hypertension, and atrial fibrillation are probable risk factors for dementia, suggesting that their treatments may influence the risk and rate of cognitive and functional decline. Moreover, ... -
Validity, Significance, Strengths, Limitations, and Evidentiary Value of Real-World Clinical Data for Combination Therapy in Alzheimer's Disease: Comparison of Efficacy and Effectiveness Studies
(S. Karger AG, 2012)Background: Randomized controlled efficacy trials (RCTs), the scientific gold standard, are required for regulatory approval of Alzheimer's disease (AD) interventions, yet provide limited information regarding real-world ...