Browsing Harvard Medical School by Keyword "Condensed-Matter Physics"
Now showing items 1-4 of 4
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Molecular Threading: Mechanical Extraction, Stretching and Placement of DNA Molecules from a Liquid-Air Interface
(Public Library of Science, 2013)We present “molecular threading”, a surface independent tip-based method for stretching and depositing single and double-stranded DNA molecules. DNA is stretched into air at a liquid-air interface, and can be subsequently ... -
Multiparametric, Longitudinal Optical Coherence Tomography Imaging Reveals Acute Injury and Chronic Recovery in Experimental Ischemic Stroke
(Public Library of Science, 2013)Progress in experimental stroke and translational medicine could be accelerated by high-resolution in vivo imaging of disease progression in the mouse cortex. Here, we introduce optical microscopic methods that monitor ... -
Raman Spectroscopy Provides a Powerful Diagnostic Tool for Accurate Determination of Albumin Glycation
(Public Library of Science, 2012)We present the first demonstration of glycated albumin detection and quantification using Raman spectroscopy without the addition of reagents. Glycated albumin is an important marker for monitoring the long-term glycemic ... -
Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label
(Public Library of Science, 2013)We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after ...