Browsing Harvard Medical School by Keyword "Experimental"
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Moderate Peep After Tracheal Lipopolysaccharide Instillation Prevents Inflammation and Modifies the Pattern of Brain Neuronal Activation
(Lippincott Williams & Wilkins, 2015)ABSTRACT Background: Ventilatory strategy and specifically positive end-expiratory pressure (PEEP) can modulate the inflammatory response and pulmonary-to-systemic translocation of lipopolysaccharide (LPS). Both inflammation ... -
Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines
(Springer US, 2016)The multicenter phase III preclinical trial concept is currently discussed to enhance the predictive value of preclinical stroke research. After public announcement, we collected a community feedback on the concept with ...