Browsing Harvard Medical School by Keyword "executive function"

Now showing items 1-7 of 7

    • Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study 

      Kubicki, Marek R.; Westin, Carl-Fredrik; Nestor, Paul Gerard; Wible, Cynthia Gayle; Frumin, Melissa; Maier, Stephan Ernst; Kikinis, Ron; Jolesz, Ferenc A.; McCarley, Robert William; Shenton, Martha Elizabeth (Elsevier BV, 2003)
      Background: Evidence suggests that a disruption in limbic system network integrity and, in particular, the cingulate gyrus (CG), may play a role in the pathophysiology of schizophrenia; however, the cingulum bundle (CB), ...

    • Failure to Modulate Attentional Control in Advanced Aging Linked to White Matter Pathology 

      Hedden, Trey; Sperling, Reisa Anne; Johnson, Keith Alan; Buckner, Randy Lee; van Dijk, Koene R. A.; Shire, Emily H. (Oxford University Press, 2012)
      Advanced aging is associated with reduced attentional control and less flexible information processing. Here, the origins of these cognitive effects were explored using a functional magnetic resonance imaging task that ...

    • Lead Exposure and Behavior Among Young Children in Chennai, India 

      Roy, Ananya; Bellinger, David C.; Hu, Howard; Schwartz, Joel David; Ettinger, Adrienne S; Wright, Robert O.; Bouchard, Maryse; Palaniappan, Kavitha; Balakrishnan, Kalpana (National Institute of Environmental Health Sciences, 2009)
      Background: Lead exposure has long been associated with deficits in IQ among children. However, few studies have assessed the impact of lead on specific domains of behavior and cognition. Objective: We evaluated the ...

    • Psychosocial Deprivation, Executive Functions, and the Emergence of Socio-Emotional Behavior Problems 

      McDermott, Jennifer Martin; Troller-Renfree, Sonya; Vanderwert, Ross; Nelson, Charles A.; Zeanah, Charles H.; Fox, Nathan A. (Frontiers Media S.A., 2013)
      Early psychosocial deprivation can negatively impact the development of executive functions (EFs). Here we explore the impact of early psychosocial deprivation on behavioral and physiological measures (i.e., event-related ...

    • Response Inhibition and Error Monitoring during a Visual Go/No-Go Task in Inuit Children Exposed to Lead, Polychlorinated Biphenyls, and Methylmercury 

      Boucher, Olivier; Burden, Matthew J.; Muckle, Gina; Saint-Amour, Dave; Ayotte, Pierre; Dewailly, Éric; Jacobson, Sandra W.; Nelson, Charles A.; Jacobson, Joseph L. (National Institute of Environmental Health Sciences, 2012)
      Background: Lead (Pb) and polychlorinated biphenyls (PCBs) are neurotoxic contaminants that have been related to impairment in response inhibition. Objectives: In this study we examined the neurophysiological correlates ...

    • Splendor in the Grass? A Pilot Study Assessing the Impact of Medical Marijuana on Executive Function 

      Gruber, Staci A.; Sagar, Kelly A.; Dahlgren, Mary K.; Racine, Megan T.; Smith, Rosemary T.; Lukas, Scott E. (Frontiers Media S.A., 2016)
      Currently, 25 states and Washington DC have enacted full medical marijuana (MMJ) programs while 18 states allow limited access to MMJ products. Limited access states permit low (or zero) tetrahydrocannabinol (THC) and high ...

    • White matter correlates of cognitive domains in normal aging with diffusion tensor imaging 

      Sasson, Efrat; Doniger, Glen M.; Pasternak, Ofer; Tarrasch, Ricardo; Assaf, Yaniv (Frontiers Media S.A., 2013)
      The ability to perform complex as well as simple cognitive tasks engages a network of brain regions that is mediated by the white matter fiber bundles connecting them. Different cognitive tasks employ distinctive white ...