Browsing Harvard Medical School by Keyword "Biocatalysis"
Now showing items 1-3 of 3
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Characterization of Mammalian Selenoprotein O: A Redox-Active Mitochondrial Protein
(Public Library of Science, 2014)Selenoproteins exhibit diverse biological functions, most of which are associated with redox control. However, the functions of approximately half of mammalian selenoproteins are not known. One such protein is Selenoprotein ... -
Diversity of Plant Methionine Sulfoxide Reductases B and Evolution of a Form Specific for Free Methionine Sulfoxide
(Public Library of Science, 2013)Methionine can be reversibly oxidized to methionine sulfoxide (MetO) under physiological conditions. Organisms evolved two distinct methionine sulfoxide reductase families (MSRA & MSRB) to repair oxidized methionine residues. ... -
Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes
(Public Library of Science, 2013)The oxidative degradation of biphenyl and polychlorinated biphenyls (PCBs) is initiated in Pandoraea pnomenusa B-356 by biphenyl dioxygenase \((BPDO_{B356})\). \(BPDO_{B356}\), a heterohexameric \((αβ)_3\) Rieske oxygenase ...