Now showing items 1-5 of 5

    • Amplitude Reduction and Phase Shifts of Melatonin, Cortisol and Other Circadian Rhythms after a Gradual Advance of Sleep and Light Exposure in Humans 

      Dijk, Derk-Jan; Duffy, Jeanne Frances; Silva, Edward J.; Shanahan, Theresa L.; Boivin, Diane B.; Czeisler, Charles Andrew (Public Library of Science, 2012)
      Background: The phase and amplitude of rhythms in physiology and behavior are generated by circadian oscillators and entrained to the 24-h day by exposure to the light-dark cycle and feedback from the sleep-wake cycle. The ...
    • EGb761, a Ginkgo Biloba Extract, is Effective against Atherosclerosis In Vitro, and in a Rat Model of Type 2 Diabetes 

      Kang, Seon Mee; Cho, Bong Jun; Shin, Hayley; Jang, Hak Chul; Park, Kyong Soo; Lim, Soo; Yoon, Ji Won; Choi, Sung Hee; Kim, Min; Park, Ho Seon; Cho, Hyun Ju; Kim, Young-Bum; Kim, Hyo Soo (Public Library of Science, 2011)
      Background: EGb761, a standardized Ginkgo biloba extract, has antioxidant and antiplatelet aggregation and thus might protect against atherosclerosis. However, molecular and functional properties of EGb761 and its major ...
    • Enhancement of Naringenin Bioavailability by Complexation with Hydroxypropoyl-β-Cyclodextrin 

      Shulman, Maria; Cohen, Merav; Soto-Gutierrez, Alejandro; Yagi, Hiroshi; Wang, Hongyun; Goldwasser, Jonathan; Lee-Parsons, Carolyn W.; Benny-Ratsaby, Ofra; Yarmush, Martin Leon; Nahmias, Yaakov (Public Library of Science, 2011)
      The abundant flavonoid aglycone, naringenin, which is responsible for the bitter taste in grapefruits, has been shown to possess hypolipidemic and anti-inflammatory effects both in vitro and in vivo. Recently, our group ...
    • The Feasibility and Impact of Delivering a Mind-Body Intervention in a Virtual World 

      Linton, Deborah A.; Bello, Heather E.; Senelly, Marco; Milik, Mariola T.; Baim, Margaret A.; Hoch, Daniel B.; Watson, Alice Joan; Jethwani, Kamal Shanker; Fricchione, Gregory Lewis; Benson, Herbert; Kvedar, Joseph Charles (Public Library of Science, 2012)
      Introduction: Mind-body medical approaches may ameliorate chronic disease. Stress reduction is particularly helpful, but face-to-face delivery systems cannot reach all those who might benefit. An online, 3-dimensional ...
    • Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome 

      Kaptchuk, Ted Jack; Friedlander, Elizabeth; Kelley, John Michael; Sanchez, M. Norma; Kokkotou, Efi G.; Singer, Joyce P.; Kowalczykowski, Magda; Miller, Franklin G.; Kirsch, Irving; Lembo, Anthony J. (Public Library of Science, 2010)
      Background: Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception. We tested whether open-label placebo (non-deceptive ...