Browsing HMS Scholarly Articles by Author "Mandal, Swadhin K."

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    • Computationally designed antibody–drug conjugates self-assembled via affinity ligands 

      Gupta, Nimish; Ansari, Aasif; Dhoke, Gaurao V.; Chilamari, Maheshwerreddy; Sivaccumar, Jwala; Kumari, Smita; Chatterjee, Snigdha; Goyal, Ravinder; Dutta, Pradip Kumar; Samarla, Mallik; Mukherjee, Madhumita; Sarkar, Arindam; Mandal, Swadhin K.; Rai, Vishal; Biswas, Goutam; Sengupta, Aniruddha; Roy, Sudip; Roy, Monideepa; Sengupta, Shiladitya (Springer Science and Business Media LLC, 2019-11-04)
      Antibody–drug conjugates (ADCs) combine the high specificity of antibodies with cytotoxic payloads. However, current strategies for the synthesis of ADCs either yield unstable or heterogeneous products or involve complex ...