Browsing HMS Scholarly Articles by Author "Rabelink, Ton J."

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    • Conversion of Mature Human β-Cells Into Glucagon-Producing α-Cells 

      Spijker, H. Siebe; Ravelli, Raimond B.G.; Mommaas-Kienhuis, A. Mieke; van Apeldoorn, Aart A.; Engelse, Marten A.; Zaldumbide, Arnaud; Bonner-Weir, Susan; Rabelink, Ton J.; Hoeben, Rob C.; Clevers, Hans; Mummery, Christine L.; Carlotti, Françoise; de Koning, Eelco J.P. (American Diabetes Association, 2013)
      Conversion of one terminally differentiated cell type into another (or transdifferentiation) usually requires the forced expression of key transcription factors. We examined the plasticity of human insulin-producing β-cells ...