Browsing HMS Scholarly Articles by Author "Goldenring, James R."
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The Recycling and Transcytotic Pathways for IgG Transport by FcRn are Distinct and Display an Inherent Polarity
Tzaban, Salit; Massol, Ramiro; Yen, Elizabeth Hechavarria; Hamman, Wendy; Frank, Scott Randy; Lapierre, Lynne A.; Hansen, Steen Henning; Goldenring, James R.; Blumberg, Richard Steven; Lencer, Wayne Isaac (Rockefeller University Press, 2009)The Fc receptor FcRn traffics immunoglobulin G (IgG) in both directions across polarized epithelial cells that line mucosal surfaces, contributing to host defense. We show that FcRn traffics IgG from either apical or ... -
The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma
Lennerz, Jochen K.M.; Kim, Seok-Hyung; Oates, Edward L.; Huh, Won Jae; Doherty, Jason M.; Tian, Xiaolin; Bredemeyer, Andrew J.; Goldenring, James R.; Lauwers, Gregory Y.; Shin, Young-Kee; Mills, Jason C. (Elsevier BV, 2010)The lack of reliable molecular markers for normal differentiated epithelial cells limits understanding of human gastric carcinogenesis. Recognized precursor lesions for gastric adenocarcinoma are intestinal metaplasia and ...