Browsing HMS Scholarly Articles by Author "Carroll, F Ivy"

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    • Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity 

      Munro, Thomas A; Berry, Loren M; Carroll, F Ivy; Zhao, Zhiyang; Carlezon, William A.; Cohen, Bruce Michael; Van't Veer, Ashlee Victoria; Beguin, Cecile Andree (BioMed Central, 2012)
      Background: Nor-BNI, GNTI and JDTic induce κ opioid antagonism that is delayed by hours and can persist for months. Other effects are transient. It has been proposed that these drugs may be slowly absorbed or distributed, ...