Browsing HMS Scholarly Articles by Author "Burrows, Anna E."
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Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence
Burrows, Anna E.; Smogorzewska, Agata; Elledge, Stephen J. (National Academy of Sciences, 2010)A variety of tumor-suppressor mechanisms exist to promote genome integrity and organismal survival. One such mechanism is cellular senescence. In response to replicative aging, DNA damage, and oncogenic stimuli, the p53 ...