Browsing HMS Scholarly Articles by Author "Yabuuchi, A."

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    • Epigenetic memory in induced pluripotent stem cells 

      Kim, K.; Doi, A.; Wen, B.; Ng, K.; Zhao, R.; Cahan, P.; Kim, J.; Aryee, M. J.; Ji, H.; Ehrlich, L.; Yabuuchi, A.; Takeuchi, A.; Cunniff, K. C.; Hongguang, H.; Mckinney-Freeman, S.; Naveiras, O.; Yoon, T. J.; Irizarry, R. A.; Jung, N.; Seita, J.; Hanna, J.; Murakami, P.; Jaenisch, R.; Weissleder, R.; Orkin, S. H.; Weissman, I. L.; Feinberg, A. P.; Daley, G. Q. (Nature Research (part of Springer Nature), 2010)
      Somatic cell nuclear transfer and transcription-factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues. Through different mechanisms and kinetics, ...