Browsing HMS Scholarly Articles by Author "Karaca-Griffin, Selen"

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    • Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike 

      Cai, Yongfei; Karaca-Griffin, Selen; Chen, Jia; Tian, Sai; Fredette, Nicholas; Linton, Christine; Rits-Volloch, Sophia; Lu, Jianming; Wagh, Kshitij; Theiler, James; Korber, Bette; Seaman, Michael; Harrison, Stephen; Carfi, Andrea; Chen, Bing (National Academy of Sciences, 2017)
      The extraordinary genetic diversity of the HIV-1 envelope spike [Env; trimeric (gp160)(3), cleaved to (gp120/gp41)(3)] poses challenges for vaccine development. Envs of different clinical isolates exhibit different ...