Browsing HMS Scholarly Articles by Author "Fang, Zi"
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Doxycycline Regulated Induction of AKT in Murine Prostate Drives Proliferation Independently of p27 Cyclin Dependent Kinase Inhibitor Downregulation
Wang, Hongyun; Xu, Youyuan; Fang, Zi; Chen, Sen; Balk, Steven Paul; Yuan, Xin (Public Library of Science, 2012)The PI3 kinase/AKT pathway has been shown to increase degradation of the p27 cyclin dependent kinase inhibitor through phosphorylation of consensus AKT sites on p27 and SKP2, and AKT driven proliferation may be checked by ...