Browsing HMS Scholarly Articles by Author "Fang, Xiaohui"
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Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome
Liu, Kathleen D; Wilson, Jennifer G; Zhuo, Hanjing; Caballero, Lizette; McMillan, Melanie L; Fang, Xiaohui; Cosgrove, Katherine; Calfee, Carolyn S; Lee, Jae-Woo; Kangelaris, Kirsten N; Gotts, Jeffrey E; Rogers, Angela J; Levitt, Joseph E; Wiener-Kronish, Jeanine P; Delucchi, Kevin L; Leavitt, Andrew D; McKenna, David H; Thompson, B Taylor; Matthay, Michael A (Springer, 2014)Background: Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling ... -
HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1
Pittet, Jean-François; Koh, Hidefumi; Fang, Xiaohui; Iles, Karen; Christiaans, Sarah; Anjun, Naseem; Wagener, Brant M.; Park, Dae Won; Zmijewski, Jaroslaw W.; Matthay, Michael A.; Roux, Jeremie (Public Library of Science, 2013)High mobility group box 1 (HMGB1) protein is a danger-signaling molecule, known to activate an inflammatory response via TLR4 and RAGE. HMGB1 can be either actively secreted or passively released from damaged alveolar ...