Browsing HMS Scholarly Articles by Author "Chang, Hsiao-Han"

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    • STAMP: Sequence tag-based analysis of microbial population dynamics 

      Abel, Sören; zur Wiesch, Pia Abel; Chang, Hsiao-Han; Davis, Brigid M.; Lipsitch, Marc; Waldor, Matthew K. (2014)
      We describe a new method (STAMP) for characterization of pathogen population dynamics during infection. STAMP analyzes the frequency changes of genetically “barcoded” organisms to quantify population bottlenecks and infer ...