Browsing HMS Scholarly Articles by Author "Braigen, Stephen Z."

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    • Niemann-Pick C1 Is Essential for Ebolavirus Replication and Pathogenesis In Vivo 

      Herbert, Andrew S.; Davidson, Cristin; Kuehne, Ana I.; Bakken, Russell; Braigen, Stephen Z.; Gunn, Kathryn E.; Whelan, Sean P.; Brummelkamp, Thijn R.; Twenhafel, Nancy A.; Chandran, Kartik; Walkley, Steven U.; Dye, John M. (American Society of Microbiology, 2015)
      ABSTRACT Recent work demonstrated that the Niemann-Pick C1 (NPC1) protein is an essential entry receptor for filoviruses. While previous studies focused on filovirus entry requirements of NPC1 in vitro, its roles in filovirus ...