Browsing HMS Scholarly Articles by Author "Barabino, Stefano"

Now showing items 1-9 of 9

    • Animal Models of Dry Eye: A Critical Assessment of Opportunities and Limitations 

      Barabino, Stefano; Dana, Reza (Association for Research in Vision and Ophthalmology (ARVO), 2004)

    • The Controlled-Environment Chamber: A New Mouse Model of Dry Eye 

      Barabino, Stefano; Shen, LinLing; Chen, Lu; Rashid, Saadia; Rolando, Maurizio; Dana, Reza (Association for Research in Vision and Ophthalmology (ARVO), 2005)
      purpose. To develop a controlled-environment chamber (CEC) for mice and verify the effects of a low-humidity setting on ocular surface signs in normal mice. methods. Eight- to 12-week-old BALB/c mice were used in a ...

    • Corneal epithelial proliferation and thickness in a mouse model of dry eye 

      Fabiani, Claudia; Barabino, Stefano; Rashid, Saadia; Dana, Reza (Elsevier BV, 2009)
      Although several studies have previously focused on the conjunctival epithelial response to surface dryness, little is known about the effect of a dry environment on corneal epithelium, which is the most clinically significant ...

    • Effect of the Ocular Microenvironment in Regulating Corneal Dendritic Cell Maturation 

      Shen, Linling; Barabino, Stefano; Taylor, Andrew W.; Dana, Reza (American Medical Association (AMA), 2007)
      Objective To determine whether the ocular anterior segment (aqueous humor and cornea) actively inhibits dendritic cell (DC) maturation. Methods Dendritic cells were injected into syngeneic corneas or conjunctivae, ...

    • Keratocyte Apoptosis and Failure of Corneal Allografts 

      Beauregard, Clay; Huq, Syed O.; Barabino, Stefano; Zhang, Qiang; Kazlauskas, Andrius; Dana, Reza (Ovid Technologies (Wolters Kluwer Health), 2006)
      Background Murine models of high-risk and low-risk corneal transplantation were used to determine the role of keratocyte apoptosis in the failure of orthotopic allogeneic corneal transplants. Materials and Methods Normal ...

    • Novel Expression and Characterization of Lymphatic Vessel Endothelial Hyaluronate Receptor 1 (LYVE-1) by Conjunctival Cells 

      Chen, Lu; Cursiefen, Claus; Barabino, Stefano; Zhang, Qiang; Dana, Reza (Association for Research in Vision and Ophthalmology (ARVO), 2005)
      Purpose. Lymphatic vessel endothelial hyaluronic acid receptor (LYVE-1) is a newly discovered lymphatic-specific marker. To date, there is no report of its expression on conjunctival cells. The purpose of this study was ...

    • Ocular surface immunity: Homeostatic mechanisms and their disruption in dry eye disease 

      Barabino, Stefano; Chen, Yihe; Chauhan, Sunil Kumar; Dana, Reza (Elsevier BV, 2012)
      The tear film, lacrimal glands, corneal and conjunctival epithelia and Meibomian glands work together as a lacrimal functional unit (LFU) to preserve the integrity and function of the ocular surface. The integrity of this ...

    • Topical Omega-3 and Omega-6 Fatty Acids for Treatment of Dry Eye 

      Rashid, Saadia; Yiping, Jin; Ecoiffier, Tatiana; Barabino, Stefano; Schaumberg, Debra Ann; Dana, Reza (American Medical Association (AMA), 2008)
      Objective To study the efficacy of topical application of alpha-linolenic acid (ALA) and linoleic acid (LA) for dry eye treatment. Methods Formulations containing ALA, LA, combined ALA and LA, or vehicle alone, were ...

    • Very Late Antigen 1 Blockade Markedly Promotes Survival of Corneal Allografts 

      Chen, Lu; Huq, Syed; Gardner, Humphrey; R. de Fougerolles, Antonin; Barabino, Stefano; Dana, Reza (American Medical Association (AMA), 2007)
      Objective To investigate the role of very late antigen 1 (VLA-1) (also known as integrin receptor α1β1) in corneal transplantation inflammation and allograft survival. Methods Cell infiltration and vasculogenesis ...