Browsing HMS Scholarly Articles by Author "Chang, Hong"
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Human B-cell Ontogeny in Humanized NOD/SCID γc\(^{null}\) Mice Generates a Diverse Yet Auto/Poly- and HIV-1 Reactive Antibody Repertoire
Chang, Hong; Biswas, Subhabrata; Tallarico, Aimee St. Clair; Sarkis, Phuong Thi Nguyen; Geng, Shusheng; Panditrao, Madhura M.; Zhu, Quan Karen; Marasco, Wayne A. (Nature Publishing Group, 2012)Characterization of the human antibody (Ab) repertoire in mouse models of the human immune system is essential to establish their relevance in translational studies. Single human B-cells were sorted from bone marrow and ...