Browsing HMS Scholarly Articles by Author "Cao, Juxiang"

Now showing items 1-1 of 1

    • Prdx1 Inhibits Tumorigenesis via Regulating PTEN/AKT Activity 

      Cao, Juxiang; Schulte, Jennifer; Knight, Alexander; Leslie, Nicholas R; Zagozdzon, Agnieszka; Bronson, Roderick Terry; Manevich, Yefim; Beeson, Craig; Neumann, Carola A (Nature Publishing Group, 2009)
      It is widely accepted that reactive oxygen species (ROS) promote tumorigenesis. However, the exact mechanisms are still unclear. As mice lacking the peroxidase peroxiredoxin1 (Prdx1) produce more cellular ROS and die ...